Dopegit: description of the medicine, indications for use and possible side effects
Dopegit (international name - methyldopa) is an antihypertensive agent that affects the vasomotor centers of the brain. It is manufactured by Egis Pharmaceutical Factory in Hungary and is available in the form of 250 mg tablets.
Indications for use of the drug are arterial hypertension. However, there are a number of contraindications in which the use of Dopegyt can be dangerous. These include hepatitis, liver cirrhosis, hepatic-renal failure, pheochromocytoma, depressive states, acute myocardial infarction, cerebrovascular diseases, severe coronary heart disease, hemolytic anemia, collagenosis and parkinsonism.
In addition, Dopegit may have side effects such as weakness, asthenia, drowsiness, dizziness, headache, arthralgia, myalgia, febrile syndrome, redness of the upper half of the body, dry mouth, inflammation of the salivary glands, glossalgia, vomiting, nausea, constipation , colitis, liver dysfunction, pancreatitis, bradycardia, edema, orthostatic hypotension, angina pectoris, heart failure, parkinsonism, facial paralysis, spontaneous choreoathetoid movements, paresthesia, impotence, decreased libido, gynecomastia, hyperprolactinemia, hemolytic anemia, thrombocytopenia and allergic reactions.
Possible interactions of Dopegit with other drugs should also be taken into account. Thus, beta blockers may increase the likelihood of developing hypertension or orthostatic hypotension. The antihypertensive effect of Dopegit can be reduced with the simultaneous use of adrenergic agonists, MAO inhibitors, tricyclic antidepressants and NSAIDs. Incompatibility with reserpine, caution when prescribing with neuroleptics, quinidine, procainamide, diacarb.
In case of an overdose of Dopegyt, acute hypotension, bradycardia, lethargy, tremor, drowsiness, nausea, vomiting, diarrhea, flatulence and intestinal atony may occur. In such cases, gastric lavage, forced diuresis and symptomatic treatment are recommended.
Before starting to use Dopegit, you must consult your doctor and strictly follow his recommendations regarding dosage and duration of treatment. It is also important to monitor your health and immediately report to your doctor any unwanted effects that may occur while taking the medicine.