Drotaverine - improvement of symptoms of spasm of smooth muscles of internal organs
Drotaverine is an antispasmodic agent, an isoquinoline derivative, produced in Russia by ALSI Pharma. The drug is used to improve the symptoms of spasm of smooth muscles of internal organs.
The dosage form of Drotaverine is tablets containing 40 mg of the active substance. The drug can be used to treat various diseases, such as cardio- and pylorospasm, chronic gastroduodenitis, peptic ulcer of the stomach and duodenum, cholelithiasis (hepatic colic), chronic cholecystitis, postcholecystectomy syndrome, hypermotor dyskinesia of the biliary tract, spastic intestinal dyskinesia, intestinal colic due to gas retention after surgery, colitis, proctitis, tenesmus, flatulence, urolithiasis (renal colic), pyelitis, spasm of cerebral vessels, coronary and peripheral arteries. The drug can also be used to weaken uterine contractions and relieve cervical spasm during childbirth, as well as to improve the symptoms of smooth muscle spasm during instrumental interventions.
Despite the effectiveness of Drotaverine, the drug has a number of contraindications and side effects. Contraindications include hypersensitivity to the components of the drug and glaucoma. Side effects include a feeling of heat, dizziness, arrhythmias, hypotension, palpitations, sweating (more often with parenteral administration), allergic dermatitis.
The drug may interact with other drugs, enhancing the effect of other antispasmodics (including m-anticholinergics) and causing hypotension when interacting with tricyclic antidepressants, quinidine, procainamide. When using Drotaverine, the reliability of spasm elimination may increase when combined with phenobarbital. The drug can also reduce the spasmogenic activity of morphine and the antiparkinsonian properties of levodopa.
An overdose of Drotaverine can lead to AV block, cardiac arrest and paralysis of the respiratory center. Therefore, it is necessary to strictly adhere to the dosage and not exceed the recommended dose.
Despite the effectiveness of Drotaverine in the treatment of spasms of smooth muscles of internal organs, before you start using it, you should consult your doctor and read the instructions for use. It is also important to consider contraindications and possible side effects of the drug. If any symptoms occur, seek medical attention immediately.