Drotaverine Hydrochloride

Drotaverine hydrochloride

Country of origin: Russia, ALSI Pharma Russia, Altaivitamins Russia, Antiviral Russia, Aspharma Russia, Bivitech Russia, Biomed Russia, Biosynthesis Russia, Bryntsalov Russia, Veropharm/Belgorod branch Russia, Irbitsky Chemical-Pharmaceutical Plant Russia, Medisorb

Pharm-Group: Antispasmodics - isoquinoline derivatives

Manufacturers: AI CN Leksredstva (Russia), ALSI Pharma (Russia), Altaivitamins (Russia), Antiviral (Russia), Asfarma (Russia), Biviteh (Russia), Biomed (Russia), Biosynthesis (Russia), Bryntsalov (Russia) , Veropharm/Belgorod branch (Russia), Irbit chemical and pharmaceutical plant

International name: Drotaverine

Synonyms: Bioshpa, Vero-Drotaverin, Droverin, Drotaverin, Drotaverin forte, Drotaverin forte, Drotaverin-AKOS, Drotaverin-KMP, Drotaverin-NS, Drotaverin-UBF, Drotaverin-FPO, No-shpa, No-shpa forte, Nosh-bra, Spazmol, Spazoverin, Spakovin

Dosage forms: substance, tablets 40 mg, injection solution 2%

Composition: Active substance - Drotaverine.

Indications for use: Spasm of smooth muscles of internal organs (cardio- and pylorospasm), chronic gastroduodenitis, peptic ulcer of the stomach and duodenum, cholelithiasis (hepatic colic), chronic cholecystitis, postcholecystectomy syndrome, hypermotor dyskinesia of the biliary tract, spastic intestinal dyskinesia, intestinal colic due to gas retention after surgery, colitis, proctitis, tenesmus, flatulence, urolithiasis (renal colic), pyelitis, spasm of cerebral vessels, coronary and peripheral arteries, the need to weaken uterine contractions and relieve cervical spasm during childbirth, smooth muscle spasm during conducting instrumental interventions

Contraindications: Hypersensitivity, glaucoma.

Side effects: Feeling of heat, dizziness, arrhythmias, hypotension, palpitations, sweating (more often with parenteral administration), allergic dermatitis.

Interaction: Strengthens (especially with intravenous administration) the effect of other antispasmodics (including m-anticholinergics), hypotension caused by tricyclic antidepressants, quinidine, novocainamide. Phenobarbital increases the reliability of eliminating spasms. Reduces the spasmogenic activity of morphine and the antiparkinsonian properties of levodopa.

Overdose: AV block, cardiac arrest, paralysis of the respiratory center.

Special instructions: Restrictions on use. Prostate adenoma, severe atherosclerosis of the coronary arteries.

Literature: Encyclopedia of Medicines 2003.