Mucosal skin exudate (synonyms: epidermal secretion, skin epidermal exudate) are proteins, mucins, lipids, as well as water-soluble electrolytes that are formed in the basal layer of keratinocytes of the epidermis and released into the dermis, including through desquamation of epithelial cells of the outer root layer. Functionally performs a barrier, protective function.
The main task of mucous skin exudate is to participate in the formation of the function of normal and surface water balance of the skin as a complex barrier of the entire organism. Mucosal exudates are natural moisturizing agents and have the ability to decompose in the depths of the epicutaneous layer under the influence of hydrolases, such as proteolytic enzymes, hepatic hydrolases and other important molecular components of post-transepidermal skin care. Significant release of MMF-type proteases makes it possible to achieve the release of large areas of skin exudate without damaging the skin barrier. When studying the composition of mucous skin exudates, it was shown that the exudate contains the following main components or fractions: glycine and alanine (transmem