Encephalitis Viral Negishi

Negishi viral encephalitis is an acute infectious disease from the group of tick-borne viral encephalitis, caused by the group B arbovirus of the same name. The clinical picture of the disease resembles two-wave spring-summer meningoencephalitis.

Negishi encephalitis occurs primarily in Japan. The causative agent of the disease is the Negishi virus, which is transmitted to humans through the bites of ticks of the genus Haemaphysalis.

The incubation period is 7-14 days. The disease begins acutely, with an increase in body temperature to 38-39°C, chills, headache, nausea, and vomiting. A few days later, a second wave of fever develops, meningeal symptoms appear - stiff neck, photophobia. Some patients experience paresis, speech and consciousness disorders.

The diagnosis is made based on the clinical picture, cerebrospinal fluid and blood tests. Treatment consists of prescribing antipyretic, painkillers, and antiviral drugs. The prognosis with timely treatment is favorable.

NEGISHI VIRAL ENCEPHALITIS

Etiology

**Negishi encephalitis virus (TBEV)** was first discovered and identified in 1969 by Japanese researcher Kenji Ogasahara. The infectious agent is widespread in Japan, China, Korea, Taiwan and Southeast Asia, North America, and many other countries in Asia and South America. TBEV is a member of the Flaviviridae family, genus Flavivirus. The causative agent of TBE belongs to the causative agents of tick-borne neuroviral infections in humans. Up to 50% of Ixodes persulcatus ticks carry the TBE virus. 1% of them infect people. The greatest risk of human infection with TBE due to tick bites occurs from April to September. TBE usually infects in the first few days after a tick bite or infection through intact skin (possibly due to the action of viruses