Wernicke encephalopathy (as well as melancholy-depressive encephalitis) is one of the rarest slowly progressive psychoorganic diseases, also called transient Wernicke encephalopathy. In the international classification of diseases it is coded under the number G93.4. In recent years, it has also been called “toxic-infectious encephalopathy”, since this form of Wernicke often occurs in the treatment of alcoholism. It is caused by a lack of thiamine, which leads to disruption of neuronal metabolism and damage to the fibers connecting nerve cells. It can occur as a complication of detoxification or against the background of various infections or prolonged malnutrition. It is more often observed in people over 50 years of age, as well as with organic pathologies of the heart, liver and kidneys. The process is most often accompanied by a mild