Fibrinoid Swelling

FN is one of the most important biochemical reactions during inflammation. FN begins after the release of prostaglandins from monocytes and represents the synthesis and secretion of fibrin from collagens that have broken down into separate threads. Subsequently, fibrin forms the basis for the formation of a blood clot, which plays a role in immune reactions, because prevents microbial cells from entering the body. The formation of a blood clot can be extremely intense and can lead to necrosis (necrosis) of tissues entering it. Under conditions of infectious inflammation, the hemostatic system functions more intensively, there is an increase in histamine secretion, the formation of fibrin threads and activation of components of the immune system.

There are both hereditary mechanisms for impaired platelet response to inflammatory mediators in children, associated with defects in receptor enzymes, and acquired ones.