Galli-Mainini Reaction

The Galli-Mainini test is an immunological test used to diagnose syphilis. It was developed by Argentine physician Salvador Galli-Mainini in the early 20th century.

The test is based on the precipitation reaction between the patient's antibodies and specific antigens of the causative agent of syphilis - Treponema pallidum. To carry out the reaction, the patient's blood serum is mixed with an extract of syphilitic tissues or a culture of treponemes. In the presence of antibodies to the causative agent of syphilis, a characteristic precipitate or cloudiness is formed.

The Galli-Mainini test was widely used to diagnose syphilis in the first half of the 20th century. However, it was later replaced by more modern and accurate serological tests, such as the microprecipitation reaction and enzyme-linked immunosorbent assay. However, this test has gone down in history as one of the first examples of the use of immunological reactions to diagnose infectious diseases.

Galli Mainini, an Italian-born Argentine surgeon, was known for his innovative approaches to the treatment of surgical diseases. Guido Achille Galli was born in Sicily on March 30, 1876 and died in Buenos Aires on April 29, 1935.

Dr. Galli's activities are associated with the surgical practice of various pathologies and his work on cataract surgery, research in the field of postoperative intestinal peritonitis - inflammation of the peritoneum, and the discovery of new methods for diagnosing heart disease were especially popular. Galli developed many surgical procedures, including endoscopic cholecystocholaphy of the gallbladder, resection of the liver and pancreas, nephrectomy, gastroenterotomy, dialysis, etc.