Hyaline Balls

Hyaline balls (HS) are large drops of hyaline (protein) formed in the cells of the liver and kidneys during hyalinosis. With this disease, hyaline accumulates in cells, which leads to their damage and death. After cell death, HS are located extracellularly and can be detected in the patient’s urine or blood.

HHs have a diameter from several micrometers to several millimeters and can be painted in different colors, depending on the composition of the hyaline. They may be clear or yellowish, pink or brown.

Hyaline balls are a sign of hyalinosis, a disease in which hyaline accumulates in the tissues of the body. Hyalinosis can be caused by various reasons, including diabetes, alcoholism, obesity and other diseases.

In hyalinosis, HS can be found not only in the liver and kidneys, but also in other organs such as the lungs, heart and brain. They can cause serious health problems such as kidney failure, heart failure and other diseases.



Hyaline balls are round or oval formations consisting of proteins that are found in the human body. They are formed in the cells of the body as a result of changes in metabolism. These balls are large drops of hyaline (hyalin protein) and are formed during hyalinosis. Hyalinoses are medical terms that describe various diseases of organs or systems. These globular proteins can be found in various organs, including the liver, kidneys and epithelium. When balls form, they do not change and do not move to other organs.

Hyaline balls can occur in a variety of conditions and often have different meanings. For example, in cases of liver disease, hyaline balls may indicate cirrhosis of the liver. In such cases, the formation of hyaline proteins in the liver allows the connective tissue inside the liver cells to escape. This improves the flow of nutrients produced by the liver to other organs and systems of the body. However, if there are too many hyaline balls in the liver, the load can become excessive and lead to an increase in their number and size.

In addition, hyaline balls can appear with kidney disease. In this case, they indicate disturbances in the filtering cells of the kidneys, which negatively affects the excretion of urine from the body. These hyaline balls can cause kidney stones and increased bladder deposits.

These globulins can also appear during the development of various cancers. The formation of giant hyaline balls is a sign of liver cancer or kidney cancer. But neither their presence nor their large size is a precursor to the diagnosis of any health problems.