Hibernoma malignant
Hibernomas are malignant tumors of the subcutaneous tissue or deep layers of the skin. The tumor consists of specifically differentiated hibernocytes (warty papillomas cells).
Etiology. Currently, the role of the mechanical factor in the development of hibernoma has not been proven. The greatest importance is attached to dysfunction of the endocrine glands and metabolic disorders (mainly disturbances in vitamin metabolism processes). In addition, hereditary and constitutional factors, age (more often observed in children), the presence of pigment and skin diseases, as well as trauma play a role. There is also a high incidence of this tumor among Uzbeks, Kurds, Tajiks, Crimean Tatars, Abkhazians and other groups of the population of Central Asia and Transcaucasia.
Clinic. The clinical picture of tumors can be very diverse. At the site of insertion of the injection needle, skin itching develops, then a tumor-like formation of a round shape forms, the soft consistency of which becomes dense over time. Sprouting of metastases into the lymph nodes and a pronounced sclerosing nature of growth, infiltration of the underlying tissues and often inflammatory processes appear. The local inflammatory reaction is insignificant, sometimes completely absent. Sometimes, in appearance, a benign lump also appears as a miliary lump, follicular