Gidyphen

Gidifen: description, use and side effects

Gidifen (international name: Clomipramine) is an antidepressant that is a non-selective inhibitor of neuronal uptake. Gidifen is produced in Germany by Arzneimittelwerk Dresden GmbH.

The dosage form of Gidifen includes tablets with a dosage of 25 mg and an injection solution also with a dosage of 25 mg. The active ingredient is Clomipramine.

Gidifen is used to treat a wide range of mental disorders, including depressive syndrome (endogenous, reactive, neurotic, organic, larvated, involutional), psychopathy, schizophrenia, chronic pain and somatic diseases, dysthymic states within the framework of psychopathic disorders in children and adolescents, obsessive disorders and phobias, catalepsy with narcolepsy, as well as bedwetting.

However, before you start taking Gidifen, you need to consider a number of contraindications. These include hypersensitivity (including other antidepressants from the dibenzazepine group), recent myocardial infarction, treatment with MAO inhibitors, pregnancy and breastfeeding (in this case, breastfeeding should be discontinued).

Side effects when using Gidifen may include dry mouth, profuse sweating, tremor, dizziness, accommodation paresis, urinary retention, orthostatic hypotension, lethargy and allergic skin reactions. Rarely, liver dysfunction, hyperpyrexia, seizures and agranulocytosis may occur.

Gidifen is incompatible with MAO inhibitors, and in case of overdose, conduction disturbances and cardiac arrhythmia, insomnia, confusion, and increased or development of phobia may occur. In this case, it is necessary to lavage the stomach, and for severe anticholinergic symptoms, physostigmine can be used intravenously or intramuscularly.

During treatment with Gidifen, you should avoid drinking alcohol. Despite its effectiveness in the treatment of mental disorders, Gidifen can cause serious side effects, so it should be taken only as prescribed by a doctor and under his supervision.

Literature: Encyclopedia of Medicines, 2003.