Adrenocorticotropic hormone

Adrenocorticotropic hormone

Adrenocorticotropic hormone (h. Adrenocorticotropicum) is a hormone that is produced by the pituitary gland and regulates the functioning of the adrenal glands. It plays an important role in regulating metabolism and adapting the body to stressful situations.

Adrenocorticotropic hormone (ACTH) is a polypeptide hormone consisting of 39 amino acids. It has a molecular weight of about 4000 daltons and consists of two parts: alpha and beta subunits. The alpha subunit contains a sequence of 21 amino acids, and the beta subunit contains 18 amino acids.

ACTH stimulates the synthesis and release of corticosteroids (cortisol and other hormones) from the adrenal glands. Corticosteroids are the main hormones that regulate metabolism, blood pressure, blood glucose levels and other body functions.

ACTH levels in the blood increase during stressful situations such as anxiety, fear, pain and injury. This is because ACTH stimulates the release of cortisol, which is the main stress hormone.

In addition, ACTH may play an important role in the development of various diseases associated with adrenal dysfunction, such as Cushing's disease and hypocortisolism.

In general, adrenocorticotropic hormone plays a key role in regulating the functioning of the adrenal glands and adapting the body to various stressful situations. Understanding its role and mechanisms of action can help in the development of new treatments for various diseases.



Adrenocorticotropic hormone (H. adrenocortropticum, ACTH or Adrenomesocorticopinemin), also known as corticotropic hormone or adrenocoicotropin, is a polypeptide hormone. It controls the function of the adrenal glands, especially their production and distribution of hormones that regulate blood pressure, heart rate, blood glucose levels, and adaptation to exercise and stress. Adenocortropine plays an important role in regulating cortisol levels, which controls the body's response to stress.