Hdpb-Reaction

The HDpb reaction is one of the most important and widely used methods in organic chemistry. It was discovered by Paul Bünning in 1853 and was named after him a few years later. Later, other researchers contributed to the study of this reaction and gave it several other names. This can cause confusion among people, so it's important to clearly name this connection every time you talk about it.

The HDpb reaction (full name “propyl hydrate diethyl ether hydrochloride”) is a chemical reaction occurring between a halogen derivative molecule with an activated hydrogen atom (H), the atoms of which are esterified with a reactive acid, usually aliphatic or polyolefinic (R1COOH), and propyl hydrate (C3H7O· H2O) isolated from the reaction mass. The reaction product is obtained due to water added to the system for condensation of polyoxyalkanes. Tetraethyl ether hydrobromide is also prepared using the same principle. To carry out the reaction, use a solution of deactivated ether in petroleum ether or pure ethyl alcohol. During the HDb reaction, the following chemicals occur: initial reagents - a halogen derivative with a free carboxyl group and propyl hydroperoxide, a concentrated aqueous solution of sodium chloride; The reaction products are stabilized bromine hydride and free propyl hydroperoxide.