Cholecystokinin

Cholecystokinin is a hormone of the gastrointestinal tract that stimulates contraction of the gallbladder and the secretion of bile, and is also involved in the regulation of gastric and intestinal motility.

Cholecystokinin was discovered in 1958 and named after the Greek words “chole” (bile) and “kineo” (movement). This hormone was first discovered in the bile of pigs and was called “bile hormone.” It was later found that cholecystokinins, which are produced in the mucous membrane of the duodenum and pancreas, play an important role in the regulation of digestion and metabolism.

One of the main functions of cholecystokinin is to stimulate contraction of the gallbladder. When food enters the stomach, cholecystokinin is released in response to the presence of bile acids in the stomach. This causes the gallbladder to contract, which promotes the release of bile into the duodenum. Bile contains bile acids, which help digest fats and promote the absorption of fat-soluble vitamins.

In addition, cholecystokinin plays an important role in regulating gastrointestinal motility. It also stimulates the secretion of gastric juice, pancreatic juice and intestinal juice. In addition, cholecystokinin may play a role in appetite control and metabolic regulation.



Cholecytokine (synonyms: lipoxygeninin, cholecystrokin) is a neuropeptide hormone of the gastrointestinal tract that is involved in the regulation of bile production and hormone secretion in the pancreatic glands. Cholecystokin is one of the most important regulators of lipid digestion and absorption, and its level greatly affects the functioning of the digestive tract. How it works?

Action of cholecystoquine Cholecystoquine is a 38 amino acid peptide that is produced primarily by adenarchitic cells of the intestine. Through the vagus nerve, it is stimulated by food and transmitted to other parts of the gastrointestinal tract. Before entering the stomach, it is transmitted through the pathway and reaches the distal part of the duodenum, where it stimulates the production of bile for several hours. After entering the mucous membrane of the bile duct, the cholecystal hormone passes into the bile duct within 5 minutes and irritates the motor neuron module in the peripheral arborescent ganglion. It controls the contraction and flow of bile through the bile duct into the small intestines.

Interactions with other substances The cytotropic properties of this hormone are necessary for moving food and facilitating its digestion. The interactions of cholecystonakin in the body with acids, calcium, free fat, water, carbohydrates and their present elements are powerful regulators that regulate digestion. In particular, interacting with the neural plexus of the stomach, the substance cholecystalnum acts on the muscles of the stomach, stimulating the release of gastric acid, and by connecting with lipases, it promotes the digestion process.

Interaction with lipids One of the very important features of cholecystrakin is that it controls the intracellular level of triglycerides (TG), free fat in cell membranes, preventing the transformation of fat and its negative effects on the body. On the other hand, the level of fat-soluble “dense” substances, unfortunately, can be increased until the liver refuses to oxidize and release cholesterol into the bloodstream. Elevated levels in the blood negatively affect the condition of the vascular wall, heart, liver and kidneys.



Cholecystokinin (CCK) is a group of peptide hormones that, in combination with fats, can promote the production of bile. And cholecysticokinaine itself is not a hormone, but it promotes the formation of the gallbladder. It follows from this that cholecystitis is important for the continuation of life. After eating, fatty fish leads to the production of CCK and bile, which did not have time to accumulate before eating it. Usually, if this bile has been deposited, it remains in the cavity of the stomach and intestines, and sooner or later will be removed from the body. Cholecysticokines improve the absorption of fats and also promote the absorption of zinc. It plays a key role in maintaining healthy skin and hair. Zinc promotes the formation of the placenta, maintains blood sugar levels, and reduces the risk of cancer and diabetes. Holakistikokini stimulates protein synthesis



Cholecystinokinin is a hormone that plays an important role in regulating digestion and metabolism in the body. It is also known as cholecystamine or cholecistroma. Cholecystin kinase is an endogenous neuropeptide that is produced in the brain and peripheral nerve endings. It is associated with the regulation of the digestive system, including the secretion of gastric juices,