Hyperaldosteronism

Hyperaldosteronism: causes, symptoms and treatment

Hyperaldosteronism is a condition in which there is an excess of the hormone aldosterone in the body. Aldosterone is a hormone produced by the adrenal cortex and plays an important role in regulating fluid and electrolyte levels in the body. It helps the kidneys retain sodium and release potassium, which affects blood pressure levels and overall health.

Hyperaldosteronism occurs when there is an excess of aldosterone, which can lead to various health problems. There are two types of hyperaldosteronism: primary and secondary.

Primary hyperaldosteronism, or Bartter's syndrome, is caused by a tumor of the adrenal cortex or hyperplasia of the adrenal cortex. This results in excess aldosterone production, which can lead to high blood pressure, electrolyte imbalance, and other health problems.

Secondary hyperaldosteronism occurs in response to other diseases such as heart failure, cirrhosis of the liver, kidney disease, or diabetes. In this case, excess aldosterone is not caused by a tumor or hyperplasia of the adrenal cortex, but by the body's reaction to other diseases.

Symptoms of hyperaldosteronism may include high blood pressure, muscle weakness, fatigue, pale skin, chest pain, and abnormal heart rhythms. With prolonged course of the disease, osteoporosis and renal failure may develop.

Diagnosis of hyperaldosteronism may require measuring aldosterone and renin levels in the blood, as well as an adrenal ultrasound or MRI. Treatment for hyperaldosteronism may include medications that block the action of aldosterone or surgical removal of an adrenal tumor.

Hyperaldosteronism is a serious condition that can lead to a variety of health problems. If you suspect hyperaldosteronism, see your doctor for diagnosis and treatment.

Hyperaldosteronism (HA, hyperaldosteronism) is a chronic disease of the endocrine system that occurs as a result of increased production of adrenal hormones - aldosterone and cortisol. When the content of specific substances in the blood goes off scale, the distribution of fluid and electrolytes is disrupted: there is a lot of blood, and urination becomes scarce. The overall metabolism decreases, and the contraction of muscle fibers in the myometrium is inhibited. The disease occurs in 5% of patients suffering from pathology of the heart and blood vessels. In women, the prevalence of pathology is one and a half times higher - 7.8%.

Adrenal gland diseases are more often recorded in young or middle-aged patients - from 35 to 50 years. The peak of diagnosis occurs between the ages of 45 and 60-65 years. Among men, the level of GA is slightly higher compared to women – 28:10. Representatives of all ethnic groups suffer equally from the pathology.

The primary change in aldosterone secretion occurs due to the proliferation of adenocorticotropic hormone (ACTH) cells; they begin to produce the hormone, which enters the blood in large quantities. When the secretory functions of the adrenal glands decrease, adrenogenital syndrome is diagnosed. At the same time, during the synthesis of aldosterone, the transition of progesterone to another form is disrupted. On average, a person secretes only 1 mcg of the hormone per day. A growing amount of aldosterone, becoming critical for the body, provokes HA and other types of disease. Often, an increase in aldosterone levels is accompanied by a decrease in the production of renal (excess substance) and androgenic (lack of) hormones. Hyperaldesteronism