Hyperproteinemia

Hyperproteinemia is a condition in which the concentration of proteins in the blood increases above normal. This disorder can be caused by various reasons, including kidney disease, liver disease, thyroid disease and other diseases.

Hyperproteinemia can lead to various symptoms such as fatigue, weakness, headaches, swelling, as well as disruption of other organs and systems of the body. However, in most cases, hyperproteinemia does not cause serious complications and does not require treatment.

To diagnose hyperproteinemia, it is necessary to conduct a blood test for protein content. If the test results show an increase in protein levels, then you need to consult a doctor to determine the cause of this disorder and prescribe appropriate treatment.

Depending on the cause of hyperproteinemia, treatment may include medications, lifestyle changes (such as reducing protein intake), and surgery.

However, it should be remembered that hyperproteinemia is only a symptom and not an independent disease, therefore, for successful treatment it is necessary to identify and eliminate the main cause of the increase in protein levels in the blood.



Hyperproteinemia is an increase in protein content in the blood serum. This condition often accompanies cardiovascular pathology and malignant neoplasms. It is asymptomatic for a long time and is discovered by chance. It is based on either synthesis disorders or blocking protein metabolism. Hyperproteinemic conditions can be divided into:

- Increase in the amount of total protein, for example, about proteinemia. It can occur with dehydration (overhydration): Quincke's edema, gestosis, chronic renal failure (uremia), dehydration due to intestinal infection: fluid retention usually occurs in the body.

Also, increased protein content may be a consequence of secondary inflammation or a tumor process. This significantly increases the risk of complications and affects the effectiveness of therapy. When the immune system is impaired, the synthesis of protein compounds increases sharply. Increased protein fractions are in the acute phase of the inflammatory process. An increase in the total amount of protein is formed due to changes in nitrogen metabolism in the body. Proteins involved in the reaction process must be removed from the body. Most often, protein synthesis shifts to protein metabolism, which causes the accumulation of nitrogenous compounds in the bloodstream. When this happens, the person is at high risk of developing hepatocellular failure. Such metabolic disturbances cause severe cardiopulmonary diseases. If a patient has a high amount of creatinine, this indicates problematic kidney function. Proteinuria can lead to the development of late toxicosis of pregnancy and hypo-anemia. The pathology of the synthesis of protein substances often appears against the background of genetic and autoimmune disorders, chronic infections and inflammatory processes.

Hyperproteinemia occurs due to the excessive release of protein molecules from damaged tissues. In patients, circulating protein increases and its composition in the blood plasma changes. All age groups of people, including infants and the elderly, can suffer from the pathology. Pathology is often diagnosed - from 90% to 95% of cases. Men suffer more often than women from hyperproteinemia (in a ratio of 57/43). The most common cases of increased protein concentration are in systemic lupus erythematosus, thyrotoxicosis, and acute vascular insufficiency. Most reported cases of high protein levels are associated with the development of cancer: leukemia, cancer metastases, lymphomas, mast cell neoplasms, thyroid and ovarian sarcoma. As an independent disease, hyperproteinemic condition is rarely diagnosed. More often it is observed at the recovery stage in chronic viral infections.