Hypoprothrombinemia (Hypoprothrombinaemid)

Hypoprothrombinemia is a pathological condition characterized by a reduced level of prothrombin (blood coagulation factor II) in the blood plasma.

Reasons for the development of hypoprothrombinemia:

1. Hereditary disorders of prothrombin synthesis.

2. Impaired absorption of vitamin K, necessary for the synthesis of prothrombin in the liver.

3. Liver diseases that interfere with the synthesis of coagulation factors.

4. The use of anticoagulants (warfarin) that suppress prothrombin synthesis.

The main symptoms of hypoprothrombinemia:

1. Increased bleeding.

2. Spontaneous hemorrhages into the skin and mucous membranes.

3. Hemorrhages after minor injuries.

4. Bleeding during and after operations.

Diagnosis is based on a coagulological blood test. Treatment consists of prescribing vitamin K supplements, transfusion of fresh frozen plasma, as well as eliminating the underlying disease that caused hypoprothrombinemia.