Ibuprofen-Akos

Country of origin - Russia

Pharm-Group - Anti-inflammatory drugs - propionic acid derivatives

Manufacturers - Sintez AKO, Kurgan (Russia)

International name - Ibuprofen

Synonyms - Apo-Ibuprofen, Bartel drugs ibuprofen, Bolinet, Bolinet Lingval, Bonifen, Bren, Brufen, Brufen retard, Burana, Dolgit, Dolgit cream, Ibalgin, Ibupron, Ibuprof, Ibuprofen, Ibuprofen Lannacher, Ibuprofen Nycomed, Ibuprofen-Teva, Ibuprofen -Hemofarm, Ibusan, Ibuprofen-Akos

Dosage forms - film-coated tablets 200 mg

Composition - Active substance: Ibuprofen.

Indications for use - Rheumatoid arthritis, reactive synovitis with deforming osteoarthritis, psoriatic arthritis, acute joint attack with gout, ankylosing spondylitis (Bechterew's disease), cervical spondylosis, Barre-Lieu syndrome (cervical migraine, vertebral artery syndrome), lumbodynia, sciatica, thoracic radicular syndrome, bursitis, tendovaginitis, myalgia, neuralgic amyotrophy, occipital and intercostal neuralgia, sprains of the ligamentous apparatus, hematomas, injuries, pain in the area of ​​the surgical wound, toothache, surgical operations in the oral cavity, panniculitis, tonsillitis, pharyngitis, laryngitis, sinusitis, rhinitis, bronchitis, pneumonia, inflammatory processes in the pelvis, disalgomenorrhea, colds, ARVI, febrile conditions, postural hypotension when taking antihypertensive drugs, nephrotic syndrome (to reduce the severity of proteinuria).

Contraindications - Hypersensitivity, peptic ulcer of the stomach and duodenum in the acute phase, nonspecific ulcerative colitis, aspirin-induced asthma, leukopenia, thrombocytopenia, hemorrhagic diathesis, severe dysfunction of the liver and kidneys, portal hypertension, arterial hypertension, heart failure, diseases of the optic nerve, scotoma, amblyopia, color vision impairment, pregnancy, breastfeeding.

Side effect - Dyspeptic disorders (nausea, heartburn, anorexia, vomiting, epigastric discomfort, flatulence, diarrhea, constipation), erosive and ulcerative lesions of the gastrointestinal tract with signs of gastrointestinal bleeding, headache, dizziness, tinnitus, insomnia, agitation , visual disturbances (blurred vision, changes in color vision), fluid retention, edema, increased blood pressure, thrombocytopenia, granulocytopenia, hemolytic anemia, Quincke's edema, broncho-obstructive syndrome, skin allergic reactions.

Interaction - Reduces the antihypertensive activity of ACE inhibitors, the natriuretic activity of furosemide and hypothiazide. May increase the toxicity of methotrexate and lithium preparations. When combined with coumarin-type anticoagulants and alcohol, it increases the risk of hemorrhagic complications, and with tableted glucocorticoids - the risk of gastrointestinal bleeding. It is not recommended to use simultaneously with acetylsalicylic acid or other NSAIDs, antidiabetic drugs, phenytoin and hormonal contraceptives. Increases the concentration of digoxin in plasma. Caffeine enhances the analgesic effect of ibuprofen.

Overdose - Symptoms: abdominal pain, nausea, vomiting, lethargy, drowsiness, depression, headache, tinnitus, metabolic acidosis, coma, acute renal failure, hypotension, bradycardia, tachycardia, atrial fibrillation and respiratory arrest. Treatment: gastric lavage, forced diuresis, hemodialysis.

Special instructions - Considering the possibility of developing NSAID gastropathy, it is prescribed with caution to elderly people with a history of gastric ulcers.