In recent years, the use of thermolability inhibitors has become popular to prevent thermal damage in tissue, especially when exposed to high temperatures. Heat-labile inhibitors are compounds that can reduce the susceptibility of tissues to thermal damage. This makes it possible to apply significant temperatures in areas such as steam sterilization and medical diagnostics.
Inhibition of heat-labile proteins makes it possible to perform various procedures that involve high temperatures, such as autoclaving proteins. These same heat-labile proteins are factors that promote bacterial growth in the gastrointestinal tract. By reducing the temperature dependence of proteins in patients, it is possible to reduce the number of bacteria that can survive even at high temperatures.
In medicine, thermolabile inhibition is used to maintain the viability of already living tissues by creating optimal operating conditions, such as oxygen or temperature control. Such methods make it possible to transfer large volumes of blood to react with oxygen. Another example is the destruction of pathogenic bacteria to treat infectious diseases. In this case, thermolabile inhibitors are prescribed to protect the animal's cells from heat.
In addition, inhibition of heat lability can also be used to preserve skin during various surgical procedures such as skin grafting. The use of an inhibitor makes it possible to slow down the erythrocyte sedimentation rate, which facilitates their migration inside the capillaries, and also to obtain reliable results when testing to determine the amount of protein in the skin.