Isoantigen

Isoantigen is an antigen that forms a natural component of human tissue. For example, antigens of the human antigenic leukocyte system are isoantigens, since they are simultaneously agglutinogens for different blood groups.

Isoantigens are proteins or glycoproteins that are expressed on the surface of cells and are unique markers for different cell types and tissues. They play an important role in the immune recognition of “self” and “foreign”, therefore they are also called transplantation antigens.

The most studied isoantigens are antigens of the AB0 system, Rh factor, HLA antigens and others. Isoantigens are widely used in medicine for blood typing, selection of donor organs for transplantation, and diagnosis of a number of diseases. Their study continues to be an urgent task in immunology and transplantology.



Isoantigens are a natural component of human body tissues. They form antigens that can be used to determine blood type or to identify body tissues. For example, antigens of the blood leukocyte system are also isoantigens.

Isoantigens can be classified according to several criteria. For example, they can be divided into ABO blood groups or Rh blood systems. There are also isoantigens that are used to determine tissue compatibility for organ transplantation.

It is important to note that isoantigens can differ between individuals and even within the same individual at different times. This may be due to various factors such as age, gender, diet and others. Therefore, when conducting blood group tests or organ transplantation, it is necessary to take into account the individual characteristics of each patient.

In general, isoantigens play an important role in medicine and biology, as they help determine tissue compatibility during blood transfusion or organ transplantation, and also help identify various diseases associated with a disorder of the immune system.



Isoantigens (ISO) are natural components of body tissues. They are parts of cell membranes and are part of the body's flow systems, which interact with all its organs and systems. From a clinical immunology perspective, isoantigen is of exceptional value. It is necessary in a medical aspect to prepare the immune system before starting a patient examination or therapy.

**Why is this important?** Isoantigen is also a regulator