Cardilopin

Cardilopin: a drug for the treatment of hypertension and angina pectoris

Cardilopine (international name - amlodipine) is a calcium channel blocker of the dihydropyridine group, which is used to treat arterial hypertension and angina pectoris.

The drug is produced in Hungary at the Egis pharmaceutical plant and is available in the form of tablets of various dosages (2.5 mg, 5 mg and 10 mg). The active substance is amlodipine.

Cardilopin lowers blood pressure and reduces workload on the heart by increasing blood flow to the heart and other organs. The drug also dilates blood vessels and reduces blood flow resistance, which improves blood circulation.

Indications for the use of Cardilopin include arterial hypertension, stable angina and vasospastic (Prinzmetal), including in patients resistant to therapy with nitrates or beta-blockers.

Cardilopin has a number of contraindications, such as hypersensitivity, arterial hypotension (less than 90 mm Hg), shock, acute myocardial infarction. The drug also has restrictions for use in cases of severe aortic stenosis, heart failure, liver dysfunction and in childhood (the safety and effectiveness of use have not been determined).

Cardilopin may cause side effects such as facial flushing, palpitations, arrhythmias, hypotension, fatigue, headache, dizziness, drowsiness, fatigue, mood changes, visual disturbances, peripheral edema, increased frequency of urination, impotence, nausea, abdominal pain , changes in bowel habits, jaundice, shortness of breath, arthralgia, myalgia, paresthesia and pain in the extremities, rashes, itching, erythema multiforme, gingival hyperplasia, gynecomastia and increased levels of liver enzymes.

Cardilopin may interact with other drugs, for example, combined use with diuretics, ACE inhibitors and beta-blockers is considered safe, but NSAIDs may reduce the antihypertensive effect. Inhalation anesthesia drugs, amiodarone, quinidine and other calcium antagonists may enhance the effect of Cardilopin.

In case of an overdose of Cardilopin, excessive peripheral vasodilation, a pronounced and prolonged decrease in blood pressure and tachycardia may be observed. Treatment includes gastric lavage, administration of activated charcoal, placing the patient in a horizontal position with elevated legs, and monitoring ra.

The use of Cardilopin during pregnancy and breastfeeding is possible if the expected effect of therapy outweighs the potential risk to the fetus. However, breastfeeding should be stopped during treatment.

Thus, Cardilopin is an effective drug for the treatment of arterial hypertension and angina, but has a number of contraindications and can cause side effects. Patients should consult a physician before starting treatment and follow his or her recommendations regarding dosage and duration of treatment.