Karyorrhexis

Karyorrhexis is the destruction of cell nuclei that occurs when they are physically or chemically damaged due to the fact that intact nuclei lose the ability to suppress the degradation of damaged cell structures. The main role of karyorrhexia is given to the action of special factors called “endogenous” or “autophages”. Due to a long-term disruption of the normal process of restoration of certain intracellular structures, which causes the decomposition of chromosomes and a number of other organelles, cellular metabolism is disrupted - cells may die. Destructive influences disrupt the integrity of the nuclear structure, resulting in karyorexia, which can lead to both the development of the disease and its cure.

Karyorrhexia is the process of destruction of the cell nucleus. It can occur both under normal conditions and in various pathologies and metabolic disorders.

One of the most common types of karyorrhexia is karyolysis - destruction of the cell nucleus under the influence of physical or chemical factors. Such factors include, for example, ultraviolet radiation, low temperatures, chemical reagents, etc. As a result of karyolysis, the cell nucleus can fragment into separate fragments that are not able to function independently and therefore the cell dies. Karyorrhexia can also be caused by various pathological processes such as tumors, infections and inflammatory reactions. For example, in cancer or infection, cells can release factors that damage the cell nucleus and lead to its destruction.

Karyorexia is an unpleasant phenomenon on the fingernails and toenails that occurs frequently. There are three types, which is directly related to the location of the affected nail. In the first case, the nail becomes dull, the line moves to the side. Then the length is greatly reduced, and the thickness of the nail decreases - and you already get horseshoes. This involves the matrix, one or more spiral arterial vessels. Most often they disappear after a couple of months, less often they never return to their previous state. If the shape of the cut is preserved, this indicates a high probability of developing leukonychia.

In the carious form of karyomalacia, this is the detachment and fall of part of the nail plate. The affected part becomes thin due to the fact that the matrix goes to the distal edge. And then she breaks. Due to the difficulty of accurately diagnosing this condition, many people confuse the carious form with a fungal infection, which is why they begin to take its treatment and, even worse, try to eliminate the consequences with their own hands. This cannot be done. It is necessary to consult a doctor - a podiatrist, who will perform a microscopy of the affected part of the nail and diagnose the true cause of the problem. Depending on this, individual treatment is prescribed, which may include physiotherapy, including UV therapy. Planar growths should be removed with nitric acid, and it is important to carry out disinfection, that is, remove dirt from the nail tissue. More use of this treatment