Karyolysis (Karyolysis)

Karyolysis (from the ancient Greek κάρυον - “nut”, “kernel” and λύσις - “dissolution”) is the process of disintegration of the cell nucleus during mitosis.

Mitosis is the process of cell division in which the nucleus of the cell divides. During mitosis, the nuclear membrane is destroyed (karyolysis), chromosomes condense, and

Karyolysis/karyolysis, or pathological mitotic index (PMI), (from the Greek Karion - cell and lysis - destruction) is a pathological sign of a malignant tumor, characterizing the number of cells of a mitotically active tumor: occurs more than 5 times in relation to the average PMI of healthy cells of a given organ B occurs during malignant degeneration due to the disintegration of the cell nucleus under the influence of oncoproteins. The biochemical mechanism of nuclear decay is not clear. Some researchers consider it as a result of the appearance of additional mitotic bodies in the cytoplasm of tumor cells, leading to the formation of multinucleated

Definition of the phenomenon Karyolysis is a process in which the nucleus of a cell is destroyed as a result of neoplastic growth or cell necrosis. During the process of karyolysis, also called "karyoptos" (from the Greek word karyo, "core"), the nucleus of the cell disintegrates. As a result of this process