Clearance

Clearance: what is it and how is it measured in medicine

Clearance is one of the key indicators used in medicine to evaluate the functioning of the kidneys and other organs responsible for removing waste from the body. This indicator allows you to determine how quickly the blood is cleared of a certain substance, and is expressed in milliliters per minute.

How is clearance measured?

Clearance is measured during a special medical test called a clearance test. Typically, this is done by venous catheterization, which allows a small amount of a special marker, such as creatinine, to be introduced into the patient's body. A urine and blood test is then performed to determine how much of the marker has been eliminated from the body over a certain period of time.

Clearance value

The clearance value can be used to determine the effectiveness of treatment, as well as to identify problems with the kidneys and other waste elimination organs. Normal clearance values ​​may vary depending on gender, age and other factors, so clearance test results should be assessed by a qualified physician.

Clearance in clinical practice

Clearance is used in clinical practice for the diagnosis and treatment of a wide range of diseases, such as chronic renal failure, diabetic nephropathy, hypertension and others. This indicator can also be useful for determining the dosage of medications, since it allows you to estimate the rate of their elimination from the body.

In conclusion, clearance is an important indicator that helps determine the efficiency of the body's waste elimination organs. It can be used to diagnose and treat various diseases, as well as to determine the dosage of medications. If you have questions or concerns about clearance, contact your doctor for advice.



Clearance is an indicator of the speed of cleansing the body of toxins and other harmful substances. Clearance is defined as the volume of solution passed through the human liver per unit of time. This indicator is important for determining doses of medications, and can also be used in the diagnosis of liver diseases. Clearance is usually measured in ml/min or ml/hour.

There are several methods for determining clearance:

* Digoxin clearance, based on determining the concentration of digoxic acid in the blood plasma before and after administration of the drug to a patient with normal liver function.

* Estimation of clearance using a single dose of a test stimulant (for example, bilirubin or rifampicin) based on changes in the concentration of substances over time.

Clearance can be measured both in healthy people and in diseases of the digestive, cardiovascular and urinary systems, and