Amoebic colitis is also called protozoal bacterial invasion of the human intestine, the clinical picture of which is dominated by manifestations of inflammation of the entire mucous membrane. The disease is caused by enteroamoeba dysentery and its tissue forms - cyst and vegetative stage. These microorganisms belong to the genus Entamoeba of the Enterobacteiriaceae family. In addition, the cylindrical thiazzoic amoeba and the thiazetzoic form, also belonging to the genus Entamoeba, cause diseases of the large intestine in humans, although their role in the pathology has not been proven and is ambiguous. The term “colitis” was proposed by M. V. Manasseina (1891) to refer to intestinal infectious diseases caused by protozoa.