Collagenosis

Collagenoses are a group of diseases characterized by diffuse damage to connective tissue. The name “collagenosis” is due to the fact that these diseases cause changes in collagen, the main protein of connective tissue.

Collagen diseases include:

1. Systemic lupus erythematosus
2. Systemic scleroderma
3. Dermatopolymyositis
4. Periarteritis nodosa
5. Rheumatoid arthritis

Common features of collagenoses are:

1. Damage to connective tissue (joints, skin, blood vessels, etc.)
2. Inflammation and tissue fibrosis
3. Impaired collagen synthesis
4. Autoimmune nature (formation of autoantibodies)

Clinical manifestations of collagenosis vary depending on the location of the lesions. This can be arthritis, myositis, vasculitis, damage to the skin and internal organs.

Diagnosis of collagenosis is based on the clinical picture, data from laboratory and instrumental studies. Treatment includes the use of glucocorticoids, cytostatics, and antimalarial drugs.

Collagen diseases are a group of diseases associated with disruption of the synthesis and structure of collagen, which leads to damage to connective tissue and the development of various symptoms. Collagenosis can affect various organs and systems of the body, including skin, joints, lungs, heart, kidneys and others.

There are several types of collagen diseases, each of which has its own characteristics and symptoms. These include systemic lupus erythematosus (SLE), scleroderma, dermatosclerosis, pulmonary fibrosis, interstitial fibrosis and others. Each of these diseases has its own causes and risk factors, and may also have a genetic predisposition.

Symptoms of collagen diseases may include skin rash, swelling, joint pain, shortness of breath, cough, weight loss and other symptoms. Treatment for collagen disease may include medications, lifestyle changes, physical therapy, and surgery. It is important to consult a doctor if symptoms of collagen disease appear in order to begin treatment promptly and prevent the development of complications.