Collagenoses Large

Collagen diseases (C) are a group of diseases that are characterized by damage to connective tissue and a progressive course. These include systemic lupus erythematosus (SLE), systemic scleroderma (SSc), dermatomyositis (DM) and periarteritis nodosa (granulomatosis) (UP).

SLE is an autoimmune disease in which the body's immune system begins to attack its own cells. This can cause damage to many organs and systems, including the skin, joints, heart, lungs and kidneys. SLE can have a progressive course, in which symptoms may worsen over time. Treatment for SLE includes immunosuppressants such as prednisolone and other drugs.

SSc is a disease that affects the skin, muscles, joints and internal organs. SSc can be progressive and lead to heart failure, renal failure and other complications. Treatment of SSc includes the use of immunosuppressants such as prednisolone and methotrexate.

DM is a disease that affects the muscles and skin. DM can be progressive and cause muscle weakness, joint swelling, and other symptoms. Treatment for DM includes the use of anti-inflammatory drugs such as corticosteroids and other medications.

UP is a granulomatous disease that can affect arteries and veins. UP can have a progressive course and lead to complications such as stroke or myocardial infarction. Treatment for UP includes the use of immunosuppressive drugs such as cyclophosphamide and other medications.

Collagen diseases require long-term and complex treatment, which may include the use of immunosuppressants and other drugs. It is important to see a doctor to diagnose and treat these diseases to prevent them from progressing and developing complications.

Collagenosis large Group K.

**Systemic diseases characterized by a progressive course and damage to vital systems** Collagen diseases are a group of connective tissue diseases that are characterized by a progressive course, various multi-symptom manifestations and involvement of vital tissues and organs in the pathological process. Classic collagen diseases are: systemic lupus erythematosus, Sjögren's disease, perioarthritis nodosa and scleroderma. This article will discuss the general characteristics of this group and the features of systemic lupus erythematosus as a classic representative of this category of diseases.

The presence of immune cells (eg, CD3+ T cells or CD4+ T cells) and plasma cells in the organs and tissues of patients with SLE suggests that these cells play an important role in the development of the disease because they express subunits of the major histosome complex