Corneoretinal Potential

Corneoretinal potential (CRP) is a bioelectric potential recorded between the cornea and retina. It reflects the activity of the retina and optic nerve in response to light stimulation.

CRP is measured using special contact lenses with built-in electrodes. When light stimulates a small area of ​​the retina, hyperpolarization of photoreceptors and bipolar cells occurs, which leads to the appearance of a negative wave of CRP. It is followed by a positive wave caused by the depolarization of retinal ganglion cells.

The amplitude and latency (delay) of CRP components depend on the functional state of photoreceptors and retinal pathways. Therefore, CRP analysis is widely used in the diagnosis of various diseases of the visual system, such as diabetic retinopathy, glaucoma, retinal degeneration, etc. Measuring CRP allows an objective assessment of the function of the retina and optic nerve.

Corneorectal potential is a term that describes the potential ability of the cornea and retina to recover when damaged or diseased. This is a very important process for the normal functioning of the eye and maintaining its health.

The cornea is the outer layer of the eye and consists of epithelium, stroma and endothelial cells. Corneal epithelial cells play an important role in protecting the eye from damage such as trauma or infection. However, if these cells are damaged or unable to perform their function properly, vision problems such as glare, blurred vision, and decreased visual acuity may occur.

The retina is the inner layer of the eye, consisting of rods and cones, which are responsible for the perception of color and light. The retina is one of the most important organs of the visual system and plays a key role in determining the brightness, contrast and clarity of images.

Corneorectal potential is based on the eye's ability to repair damaged tissue such as epithelial cells and nerve fibers. This mechanism can help treat various diseases such as corneal trauma, corneal infections, or degenerative processes such as age-related macular degeneration.

In the course of research, it was discovered that when the cornea is injured, its epithelial cells are primarily affected. If these cells experience severe damage or die, this results in decreased vision and loss of light sensitivity. Corneal infections are another factor that damages epithelial cells, which can lead to permanent and irreversible damage to the cornea. Degenerative processes in the retina can also damage its cellular structures and cause loss of color sensitivity and dark adaptation.

The eye's ability to regenerate is a physiological mechanism that occurs as a result of the interaction between the cells of the cornea, retina and nearby tissues. Under different conditions, the cornea and retina can stimulate or suppress the growth of new cells and the development of neurons. These mechanisms can improve recovery and regeneration of the eye even after severe damage. They also help prevent further vision loss and maintain eye health.

Modern treatment methods based on the corneorectal potential can significantly improve the functional state of the cornea,