Xyzal

nameLevocetirizine
Dosage forms: film-coated tablets 5 mg
Composition Active substance: levocetirizine dihydrochloride. Excipients: microcrystalline cellulose, lactose monohydrate, colloidal silicon anhydrite, magnesium stearate; shell: hypromelose (E464), titanium dioxide (E171), macrogol-400.
Indications for use For adults and children over 6 years of age: treatment of symptoms of year-round and seasonal allergic rhinitis and allergic conjunctivitis, such as itching, sneezing, rhinorrhea, lacrimation, conjunctival hyperemia; hay fever (hay fever); urticaria, including chronic idiopathic urticaria, Quincke's edema; and other allergic dermatoses, accompanied by itching and rashes.
Contraindications Hypersensitivity to any of the components of the drug or piperazine derivatives. Severe form of chronic renal failure (creatinine clearance less than 10 ml/min). Children (up to 6 years). With caution - chronic renal failure (correction of the dosage regimen is required), elderly age (possible decrease in glomerular filtration). The drug is not recommended to be prescribed women during pregnancy and breastfeeding.
Side effects: Headache, drowsiness, dry mouth, fatigue. Rarely - migraine, dizziness, dyspeptic disorders, allergic reactions (angioedema, rash, urticaria, itching).
Interaction Combined use with macrolides or ketoconazole did not cause significant changes in the ECG. Co-administration with theophylline (400 mg/day) reduces the total clearance of levocetirizine by 16% (theophylline kinetics does not change). When used in therapeutic doses, no data on interaction with alcohol have been obtained. However, it is necessary to refrain from drinking alcoholic beverages.
Overdose Symptoms: may be accompanied by signs of intoxication in the form of drowsiness; in children, an overdose of the drug may be accompanied by anxiety and increased irritability. Treatment: if symptoms of overdose appear (especially in children), the drug should be stopped and symptomatic therapy is carried out. In case of severe overdose, hospitalization and intensive care may be required.

In general, levocetirizine is a safe and effective drug for the treatment of allergic diseases in adults and children over 6 years of age. However, before starting use, you should familiarize yourself with contraindications and side effects, and also consult your doctor.