Leptomeningitis is an acute or chronic infectious-allergic lesion of the soft meninges. They are caused by hematogenous, lymphogenous or direct entry of the pathogen into the cerebrospinal fluid, where it actively multiplies with a decrease in the immunobiological forces of the body. These infections also include toxoplasma meningoencephalitis. As an independent disease in humans, it is rare due to superinfection, becoming a complication of HIV infection in which there is a high incidence of infection. In young people, this type of infection occurs as a monovalent disease characterized by a specific structure