Plasmacellular lymphogranuloma

Plasmocellular lymphogranuloma: Understanding and treatment

Lymphogranuloma plasmocellularis, also known as plasmacellular lymphogranuloma, is a rare disease that affects the lymphatic system and causes the formation of tumors composed of plasma cells and lymphocytes. This disease usually appears as tumors in the lymph nodes, but can also affect other organs and tissues.

The reasons for the development of plasmacellular lymphogranuloma are not fully understood. Some studies point to possible immunological, viral or genetic factors. However, the exact mechanisms of development of this disease remain the subject of research.

Symptoms of plasmacellular lymphogranuloma may vary depending on the location of the lesion and the extent of the disease. Typically, patients complain of an increase in the size of the lymph nodes, which can be painful on palpation. In some cases, general symptoms such as fever, weight loss and fatigue may occur.

Diagnosis of lymphogranuloma plasmacellularis involves various research methods such as lymph node biopsy, cytological analysis, immunohistochemical studies and educational methods such as computed tomography (CT) or magnetic resonance imaging (MRI).

Treatment for lymphogranuloma lymphogranuloma is usually based on a combination of methods such as chemotherapy, radiation therapy and surgery. The choice of optimal treatment depends on many factors, including the extent of the disease, the patient's age and overall health. Due to the rarity of this disease, optimal treatment approaches are still a matter of further research and clinical observation.

The prognosis for patients with lymphogranuloma plasmacellular depends on the stage of the disease and the effectiveness of treatment. In some cases, it is possible to achieve complete recovery or long-term remission, especially with early diagnosis and timely treatment. However, in some patients the disease can be aggressive and have a poor prognosis.

In conclusion, lymphogranuloma plasmacellularis is a rare disease characterized by the formation of tumors from plasma cells and lymphocytes in the lymphatic system. Its exact causes of development are still unclear and further research is required. Diagnosis is usually based on biopsy and additional testing. Treatment involves a combination of chemotherapy, radiation therapy and surgery, and can be individualized depending on the patient. The prognosis depends on the stage of the disease and the effectiveness of treatment.

Overall, plasmacellular lymphogranuloma remains a complex and rare pathology that requires further research to better understand its causes, mechanisms of development and optimal treatment methods.



Lymph nodes are nodules of various sizes located in the thickness of the tissue. These are the ones that need to be compared with these old, shriveled mushrooms - the focal points of the lesion in primary lymphogranum.

The nodes are dense, doughy to the touch, yellowish-gray in color, tightly fused to the walls of the lymphatic vessels. When cut, the tumor breaks up into whitish-pink layers that crumble and crumble (stromatosis). The last stages of node disintegration are mucusing of the stroma, cell separation (fragility, fork-shaped cell shape) and the formation of areas of tumor tissue disintegration. Remains of cell nuclei and fibroids along the stroma impart necrotic changes to the lesion. Clinically the disease