Mabtera

MabThera: Antitumor immunoglobulin to fight lymphoma

MabThera is an antitumor immunoglobulin that is used to treat certain types of lymphoma. It is produced by Hoffmann-La Roche and is available in Switzerland and the United States of America.

The dosage form of MabThera is presented in the form of a concentrate for the preparation of an infusion solution. Two dosages are available: 100 mg/10 ml and 500 mg/50 ml. The active substance of the drug is rituximab.

Indications for use of MabThera include the treatment of B-cell non-Hodgkin lymphomas in adult patients. This may be a relapsed or chemoresistant form of low-grade lymphoma or follicular lymphoma.

However, there are some contraindications to the use of MabThera. For example, patients with hypersensitivity to any component of the drug or to mouse proteins should not use it. It is also not recommended to prescribe MabThera during breastfeeding.

MabThera can cause various side effects. Some of them include weakness, dizziness, headaches, pain in various parts of the body, sleep disturbances, nausea, vomiting, diarrhea, hypertension, anemia and infections. These are just some of the possible side effects, and each patient may react differently.

It is important to consider the interaction of MabThera with other drugs. It may increase the risk of allergic reactions in patients who already have anti-mouse proteins or anti-chimeric antibodies.

Overdose of MabThera has not been described, but if any problems occur, consult a doctor.

There are some special instructions that should be taken into account when using MabThera. Patients with a high tumor burden (foci larger than 10 cm), cardiovascular disease, neutropenia, pregnancy or pediatric patients should be prescribed the drug with caution. Patients should use reliable methods of contraception during treatment and for one year after treatment if they are women of childbearing potential.

In conclusion, MabThera is an antitumor immunoglobulin that is widely used to treat certain types of lymphoma. It may have side effects and should be used under medical supervision. It is important to discuss all indications, contraindications, possible side effects and interactions with other medications with your doctor before starting treatment with MabThera.