Mastocytosis Cutaneous-Visceral

Visceral cutaneous mastocytosis is a pathology characterized by an excessive number of mast cells in various tissues of the body, most often found in children. It is manifested by disturbances in the functioning of the nervous system, the occurrence of edema and tissue atrophy.

Mastocytosis is a group of diseases associated with pathological changes in mast (mushroom) cells. The morphological changes are based on hyperplasia or proliferation of protoplasmic processes caused by unregulated cell division. Depending on the location of mast cell elements, various forms of mastocytosis can be distinguished. - the skin form is manifested by multiple pale brown spots with many small nodules measuring 1-2 mm. Sometimes the disease occurs with a predominance of the bronchial or gastrointestinal form, manifested by bronchial asthma, rash on the face, urticaria, and painful itching. Diagnostics: total biopsy of affected tissues or their fragments; To confirm the diagnosis, histological and cytological studies and comparative characteristics of the data obtained are often required. Treatment options depend on the type of disease and may include drug therapy, surgery, and immunotherapy. However, some types of mast cells are still considered incurable.