Metallosis Eyes

The eye, being the most developed part of the human brain, must clearly and clearly perceive the surrounding reality. But there are often cases when our eyes can see something more or different from the norm. While this can happen and is often mentioned in movies or stories, it doesn't always mean it's true. Metal-ohunos is an example of incorrect perception of specific information by the eyes.

The reasons for this are unclear and remain a subject of debate among scientists. Only risk factors for the development of ocular metallosis are known. Among them there are hereditary causes, for example, the transmission of mutations to the KCNJ13 gene (predictor) with the subsequent formation of severe forms of ocular metalaconus. Diseases that affect the pigment epithelial cells of the retina and optic nerve sometimes provoke the formation of cataracts or inflammation of the vitreous body (meningitis). In addition, some refractive errors (eg, astigmatism) alter light rays and increase artifacts in peripheral vision associated with depletion of light-reflecting structures in the retina. The incidence of metalloconus increases with age, regardless of other factors. Recent studies have found that metallosis may occur due to chronic diseases such as diabetes or autoimmune diseases including lupus and Sjögren's syndrome. Mercury poisoning can also lead to metallosis. Recently, a report was published on the existence of an association between ocular metallosis and the presence of certain polymorphisms in the LOX (oxygenase) gene; one of them reflects the increased sensitivity of the eye to the effects of oxidants on the retinal pigment epithelium, the other increases the clinical manifestations of the disease. Risk factors include the presence of hereditary eye diseases, the use of contact lenses, taking medications and a number of jobs in hazardous industries.

Ocular metallosis is associated with a number of optical properties of the ocular substance and biochemical changes in the retinal pigment epithelium due to tissue damage or



Metallosis of the eye. Copper, chromium, nickel, lead

People say that there are no worse diseases than eye and ear diseases. Therefore, any disease of these organs of vision is immediately noticed and upsets the person. The eye is a powerful analyzer of light flux, its visual center. And its role and participation in all mental processes is very significant. Therefore, such a loss of the sense of vision always has a sharp negative effect on the human psyche and complicates the course of his life.

**Metallosis of the eye** – **this** is a gradual change in the structure of the lens under the influence of various factors: chemical, mechanical, physical, etc. There are two types of chemical metallosis of the lens: jelly-like metal deposits and metachromatic foci. The former are uneven clouding of the inner or outer capsule of the lens, the latter are inflammatory changes in the vitreous body and the pupil area around metal deposits. Damage to the eye by metal salts is caused by many chemicals used to treat glaucoma in patients, hypertension in a healthy person, and conditions with increased intraocular fluid pressure: atropine, pilocarpine chloride, dipivefrin. Often salts of copper and cobalt and other metals enter the eye with the vitreous body (the fluid that fills the eye). In patients after extracapsular cataract extraction surgery, after retinal detachment, phosphates, bismuth, silver, etc. can penetrate into the blood. These substances are then carried by the bloodstream, tissue fluid and lymph to all organs and tissues, including the lens. With a high concentration of metal salts in the blood, they penetrate into the eye tissue even through an intact cornea. In such cases, metal deposition occurs directly in the tissues of the eye; if the patency of the cornea is preserved, then metallized droplets (plasma inclusions) are deposited along it.

The eyes of different people are individual and react equally to the same metal. But it is noted that there are “metallose” people who more often than others suffer from the consequences of exposure to certain chemical pollutants both inside the body (with a tendency to allergic reactions or