Mianserin (Mianserin)

Mianserin is a medicinal substance used to reduce moderate to severe depression and anxiety in the patient. Prescribed internally. Side effects are usually milder than with other potent antidepressants; The main side effect is drowsiness.

Mianserin belongs to the group of tetracyclic antidepressants. It blocks α2-adrenergic receptors in the brain, which leads to increased release of norepinephrine and serotonin, neurotransmitters that play an important role in regulating mood and emotions.

Mianserin is effective in the treatment of depressive disorders of varying severity. It also has a mild sedative effect, so it is often prescribed to patients with anxiety disorders and sleep disorders.

The drug is available in tablets under the trade names "Bolvidon" and "Norval". The dose of mianserin is selected individually depending on the patient’s condition. The course of treatment usually lasts several weeks or months.

Mianserin is a medication that is used to treat moderate to severe depression and anxiety in patients. It is a potent antidepressant and is usually given orally.

Mianserin has fewer side effects than other strong antidepressants, but may still cause drowsiness in some patients. One of the trade names for mianserin is Bolvidone.

It is important to note that treatment of depression and anxiety with medications should be carried out under the supervision of a doctor and only after consultation with him. Self-medication can be dangerous and lead to serious consequences.

Mianzepin: history of appearance, characteristics, composition, formula and principle of action

Mianzepine (INN: mianserin) is a medicine used to treat various mental disorders such as depression and anxiety. It is an tidepressant and is also used as an anti-anemic therapy. Let's look at the purpose of this medicine, its pharmacological action, side effects, contraindications, cross-reaction with other drugs and ways of overdose of mianzepine.

Mechanism of action The medicine has a mild activating effect on the central nervous system: it suppresses (even weaker in strength than other antidepressant drugs: imipramine) the desire for suicide, reduces the excitability of the sympathetic nervous system, improves mood and reduces distress of vegetative origin. Among other properties of the drug, it should be noted that it is a short-term anticholinergic agent. It is used as an antidepressant, for example for melancholia, and also: - for the prevention and treatment of psychomotor disorders (motor (psychomotor) disorders) caused by Parkinson's disease (left-sided disease, postencephalitic parkinsonism, encephalitis or other infectious diseases of the brain, Little's disease, syringobulbia, amnesia (forgetfulness), dementia (dementia), asthenia (asthenic condition), cerebral coma, Gettington's chorea (progressive shaking palsy), thyroid disorder, akathisia (attention disorder)). A lyophilisate is produced and administered orally at a dose of 3-4 mg/day. In the morning; as an antipsychotic for preoperative preparation and postoperative treatment for symptoms of fear - 2-6 mg at bedtime. For insomnia caused by Parkinson's disease, 50-100 mg an hour before bedtime. Large doses should only be used in a hospital setting. The duration of the course of treatment and dosage regimen are determined by the doctor, taking into account the patient’s condition. The side effects of mianserin are known to all patients taking this drug. These include a feeling of weakness, drowsiness, fatigue, a feeling of heaviness in the head, headache, dizziness, sleep disturbances, dry mouth, changes in appetite, stomach pain, stool retention, chills, nervousness, mental disorders, exacerbation of neurological