Minus Strain RNA

Minus-strand RNA (miRNA) is a polyribonucleotide strand that is part of the viral RNA and does not perform the functions of messenger RNA. It serves as a template for the synthesis of plus-strand RNA during viral replication.

Minus-strand RNA can be found in a variety of viral genomes, including animal, plant, and bacterial viruses. In most cases, it is part of the viral replication complex and is involved in the synthesis of new copies of viral RNA. However, in some cases, the minus strand can also perform other functions, such as regulating host gene expression.

MiRNA plays an important role in the regulation of gene expression in animals and plants. They can interact with mRNA (messenger RNA) and change its expression level. This can lead to various biological effects, such as suppression or enhancement of gene transcription, as well as changes in protein levels.

In addition, miRNAs may influence the regulation of other genes that are not associated with viral infection. For example, they can influence the expression of genes involved in cell development and differentiation.

Research on miRNAs is ongoing and their role in biology is still being explored. However, it is already clear that miRNAs are an important component of viral infection and can be of great importance for understanding the mechanisms of gene replication and regulation.



RNA belongs to molecules made of polymeric acids and is one of the forms of nucleic acids. It belongs to macromolecular biopolymers and includes many monomers - ribosyls. These polymers consist of one long turn of polymer and contain anticodons and one residual ribonucleoside attached at the 3'-OH end. As for the “minus” RNA chains, they are included in the replicating form of a number of viruses and do not contain ribic acids. They are an integral part of the ribosome plus the RNA of the virus, but do not participate in the transcription process (in which information is encoded by the RNA nucleotide sequence). Key function minus RNA strand, functioning as messenger RNA for cRNA and protein synthesis, consisting of amino acids that are encoded by messenger RNA depending on the organism. The formation of new RNA molecules is carried out by “superposing” a DNA exomatrix chain on an RNA + matrix subunit. The encoded information is transferred to the cell by attaching to the matrix chain with the help of ribohydrolase, which catalyzes the hydrolysis of the activated phosphoric acid residue - deamination of the phosphodiester bond of the RNA molecule - virus (Fig. 2). This process is called translation, and RNA is used as an intermediate to produce protein molecules that serve as the structural components of the virus. In terms of pattern recognition, nucleic acid transcription within the body causes misreading of the viral RNAome messenger portion, which is the cause of viral transmission and infection.

The functions and structural components of minus RNA include protecting DNA replication. It is also responsible for blocking immune control response systems, protects capsids during division, and also helps to increase the rate of subsequent onset of the syndrome