Murphy Symptom

__Murphy symptom__ is one of the symptoms observed in diffuse connective tissue diseases. An effusion is detected in the serous cavities and pericardium, which does not resolve and can be quite large.

Symptoms:

Painful areas or symptoms on palpation are observed in the area of ​​innervation of the III, IV, V, VI intercostal nerves and lower phrenic nerves (history of cardiomegaly), chest pain, hiccups, nausea, vomiting, pharyngolaryngitis, persistent constipation, arrhythmia, expansion of the borders of the heart , pericardial friction noise, effusions in the pleural cavities. Clinical manifestations can occur episodically or for a long time, and are often difficult to treat. Against the background of exacerbation, characteristic signs are noted. In some patients, the phenomena progress and become irreversible. Malignant purulent-septic complications may appear. Often, increased RF activity, myocardial damage (thickening of the heart muscle), and sclerotic changes in the abdominal aorta are detected in the blood.