Necrosis of the kidneys Medullary

Kidney necrosis is damage to the organ with necrotization of the parenchyma. Most often this is a secondary pathological condition, but can have an independent course. In the latter case, the disease is also accompanied by destruction of the fibrous capsule of the kidney and pyelocaliceal system, as well as peritumoral tissues. The causes of the disease are infectious and non-infectious, congenital and acquired. A separate form is the hematogenous, or secondary form of the disease. Necrosis is characterized by a slow development and often wavy course, in which periods of exacerbation are replaced by relative calm. Periods of rest alternate with exacerbation and deterioration of the condition until the end stage of renal failure. The sinus of the medullary component of the kidney, including the renal sinus, collecting ducts, pelvis and calyces, suffers predominantly from necrotic changes. In 60% of patients, the cortex is affected. The pathological process is accompanied by an inflammatory reaction, swelling of the surrounding tissues, the appearance of ulcerative defects and urinary fistulas. Necrotic changes in the kidney are accompanied by urodynamic disturbances that impair the blood supply to the organ, up to the development of life-threatening conditions such as anuria or collapse. Treatment depends on the cause that provoked the pathological condition. This



Kidney necrosis is a pathological process that manifests itself in various forms, extent and depth of damage to the renal tissue. Renal necrosis can be partial or total, affecting one organ (solitary, single) or several (multiple). Nephritis of any etiology usually develops according to the hypocronic type, damage to the parenchyma due to progressive atherosclerosis - according to the hypertrophic type, and due to toxicosis of pregnant women - according to the mixed type. Necrosis of the renal tubules is observed only in cases of functional renal failure (ischemia, poisoning, shock) and quickly stops after eliminating the cause of the disorder.