Neural Crest

Neural Crest: what is it and how is it formed

The Neural Crest is a structure that plays an important role in the development of the embryonic nervous system of animals. It consists of two outgrowths that form under the neural folds. Neural crests are strands of cells that, after the neural groove closes into the neural tube, turn into ganglion plates located on the side of the neural tube and moving away from it. These plates further differentiate into various cell types, including neurons, glial cells, and chromaffin cells.

The crest nerve is one of the most amazing and mysterious formations in developmental biology. It is formed through a complex process that involves many steps, including induction, epithelial-mesenchymal transition and cell migration.

Induction is a process in which one group of cells influences another group of cells, resulting in a change in their fate. In the case of the neural crest, induction occurs through the interaction of epidermal cells and the neural tube.

Epithelial-mesenchymal transition is a process in which epithelial cells acquire mesenchymal properties and begin to migrate into tissues. In the case of nerve crest, this occurs through the action of various signaling molecules, including growth factors and cell adhesion molecules.

Cell migration is the process by which cells move into tissues to form specific structures and organs. In the case of the neural crest, this occurs through the migration of ganglion plates, which further differentiate into different cell types.

Neurons of the spinal and sympathetic ganglia, chromaffin cells of the adrenal medulla and paraganglia are formed from the cells of the ganglion plates. Thus, the crest nerve plays an important role in the formation of the nervous system and the regulation of important body functions such as cardiovascular activity, digestion and body temperature regulation.

In conclusion, the neural crest is one of the most fascinating structures in developmental biology. It is formed through a complex process that involves many steps, including induction, epithelial-mesenchymal transition and cell migration. The nerve crest plays an important role in the formation of the nervous system and the regulation of various body functions. Its study can lead to new discoveries and understanding of the mechanisms of development of organisms.



The neural crest (or Neural Crest) is two outgrowths of cells that form under the neural folds in the early stages of development of the nervous system. These projections are part of the development of the nervous system, which begins with the formation of the neural tube.

Neural crests are strands of cells located along the periphery of the neural tube. They are formed after the neural groove closes into the neural tube. The neural crests extend away from the neural tube and become ganglion plates.

Neurons of the spinal and sympathetic regions, as well as chromaffinocytes of the brain, are formed from the cells of the ganglion plate. In addition, paraganglia also originate from neural crests.

Thus, neural crests play an important role in the development of the nervous system and the formation of various types of cells involved in regulating body functions.



Neural crest cells are clusters of cells located under the neural crest of the notochord. The sheath connects the neural crest to the neural tube, which runs along the back. Pectineal cells are not associated with the growth of the nervous system of the embryo; they play an important role in education and development