Neurotrophic

Neurotrophic - relating to the growth and trophism of nervous tissue in the body.

Neurotrophic factors are proteins that stimulate the development, growth and survival of nerve cells. They are important for the normal functioning of the nervous system.

Neurotrophins are a family of neurotrophic factors that include nerve growth factor (NGF), neurotrophin-3, neurotrophin-4/5, and brain-derived neurotrophic factor (BDNF). They regulate differentiation, growth of axons and dendrites, and synaptic plasticity of nerve cells.

Disturbances in the synthesis and transport of neurotrophins can lead to the development of certain neurological and mental diseases. Therefore, the study of neurotrophic factors is important for understanding the pathogenesis and finding treatments for such disorders.

Neurotrophic factors (NFs) are a family of proteins that play key roles in regulating the growth and function of neurons and other cell types in the nervous system. They were originally described in the 1980s as factors that stimulate neuronal growth and differentiation, and NFs have since been found to also play an important role in maintaining neuronal viability under conditions of stress and inflammation.

Neurotrophic factors can be divided into two main groups: neurotrophins and neuromodulators. Neurotrophins include proteins such as Brain-derived neurotrophic factor (BDNF), Nerve growth factor (NGF), and Neurotrophin-3 (NT-3), which promote neuronal survival and growth. They release neurons, and when they are released, they act on other neurons in the brain.

On the other hand, neuromodulators such as glutamate, glycine, acetylcholine, gamma-aminobutyric acid (GABA) and endogenous opioids also play an important role in the regulation of neurons, but act on them differently. Glutamate and glycine excite neurons, while GABA, endogenous opioids and acetylcholine have an inhibitory effect.

Although neurotrophic factors and neuromodulators act in different areas of the brain, they are closely related and interact to ensure optimal functioning of the nervous system. For example, BDNF and NGF stimulate neuronal survival and growth, while glutamate and acetylcholine can enhance their activity.

Thus, neurotrophic factors are key regulators of the growth and functioning of nervous tissue. They ensure the survival and repair of damaged neurons and also support normal brain function. Understanding the mechanisms that regulate the production and action of neurotrophic factors may be important for the development of new methods

**Introduction**

Neurotrophic factors (NF), also known as nerve growth factors (NGF), are proteins that regulate the growth, development and regeneration of nerves in our body. These proteins can have both positive and negative effects on the health of the nervous system. Recent studies have shown that the neurotrophic effects of drugs used in the treatment of mental disorders may be associated with their effect on the level of NF in brain tissue. This suggests that the results of these studies may also have implications for the underlying causes of these disorders. In this article we will look at some of the most well-known neurotrophic factors and their roles in the development and functioning of the nervous system, as well as the relationship between levels