Islets Of Langerhans

The islets of Langerhans, or pancreatic islets, are small clusters of cells that are located throughout the pancreas and secrete two hormones - insulin and glucagon - that play an important role in regulating blood glucose levels.

There are three main histological cell types that make up the islets of Langerhans: alpha cells, beta cells, and delta cells. Alpha cells produce glucagon and are the most numerous; beta cells produce insulin; and delta cells secrete somatostatin, which suppresses the activity of other islet cells.

Insulin is the main hormone that regulates blood glucose levels, and its secretion depends on the level of glucose in the body. When glucose levels in the body drop, beta cells in the islets of Langerhans begin to produce insulin, which helps the cells absorb glucose from the blood and convert it into energy.

Glucagon, on the other hand, is a hormone that increases blood glucose levels and is used in situations where the body needs a rapid increase in glucose levels, such as during exercise or stress.

Thus, the islets of Langerhans play a key role in regulating blood glucose levels through the secretion of insulin and glucagon. Disruption of the islet of Langerhans can lead to the development of diabetes mellitus and other diseases.



The islets of Langerhans are small clusters of cells that are found in the pancreas and play an important role in regulating blood glucose levels. These islets are called “Islets of Langerhans”, after the German scientist Paul Langerhans, who first described them in 1869.

The islets of Langerhans secrete two hormones - insulin and glucagon - which regulate blood glucose levels and ensure normal functioning of the body. Insulin helps cells use glucose for energy, and glucagon stimulates the production of glucose from fat and protein.

There are three types of cells that make up the islets of Langerhans: alpha, beta and delta cells. Alpha cells produce glucagon and secrete it into the blood when glucose levels in the body rise. Beta cells, on the other hand, produce insulin and secrete it when glucose levels drop. Delta cells secrete the hormone somatostatin, which suppresses the secretion of insulin and glucagon.

The importance of the islets of Langerhans for the body is that they regulate blood sugar levels, which allows the body to function properly and avoid the development of diabetes and other metabolic diseases.