Pachydermatospis is an inherited disease characterized by thickening of the skin and soft tissues of the arms, legs, face and neck. Dark blue or purple growths appear that do not hurt. These formations can lead to deformation of the limbs and impaired mobility of the fingers. They can also cause breathing problems such as wheezing at night or during the day in some patients. Treatment for pachyderatosp is carried out by surgical removal of the formations or treatment with drug therapy that supports body functions. It is important to remember that all patients require an individual approach to treatment depending on the severity of the disease and possible complications.