Panmyelosis

**Panmyelosis is a common pathology of the bone marrow.** Pay attention to the structure of the nuclei of the formed elements, evaluate the ratio of young and old cells, remember the existence of blast cells. The blast transforms into a granulocytic cell or megaloblast. A blast cell can also be formed from megakaryoblasts. Both blastemia and metamyeloid sarcoma have atypical multinucleated cells and amorphous basophilic substance. In bone marrow aspirate, blasts or mature cells are absent or absent, whereas in the myelogram 5-10% are