Paraganglion Chromaffin

Paraganglia Chromaffin

Paraganglia are a group of neuroendocrine cells that are found in humans and animals and are responsible for the production of catecholamines (adrenaline and norepinephrine). Catecholamines are important neurotransmitters involved in the regulation of various body functions such as heart rate, blood pressure, respiration, metabolism, etc.

One type of paraganglia is the Chromaffin paraganglia. This paraganglion consists of chromaffinocytes, which produce catecholamines - adrenaline and norepinephrine. Chromaffinocytes are found in the adrenal medulla and release catecholamines into the bloodstream.

Chromaffinocytes are part of the endocrine system, which regulates various body functions. They also play an important role in regulating blood pressure and heart rate, as well as in the body's adaptation to stressful situations.

If the functioning of chromaffinocytes is disrupted, various diseases associated with impaired production of catecholamines can occur. For example, with hyperfunction of chromaffin cells, hyperactivity of the parasympathetic nervous system can occur, which leads to low blood pressure, slow heart rate and other disorders.

In addition, chromaffin paraganglia may be involved in the development of certain diseases, such as adrenal cancer, Parkinson's disease and others.

In general, chromaffin paraganglia play an important role in many processes occurring in the body, and disruption of their function can lead to serious health consequences.

Paraganglia Chromaffin

Chromaffin paraganglia (also chromaffinocyte) are a type of chromaffin-containing cells along the lumbar vein that supplies the thymus. The average human chromaffin paraganglins make up about 2 percent of the total number of chromaffin polygons.

Where did they come from Paragaglion chromaffin is formed from neural crest cells, which are located in the embryonic cervical ganglion and are transmitted along afferent pathways to the area of ​​sympathetic innervation of the heart. This is known as the Cunningham core. They also have precursor cells, which are divided into melanin-producing and catecholamine cells, but melanins are of particular importance here and under general conditions produce chromatophores. Under stress, paragaglion chromaffin precursor cells will most likely become chromaffin, although they can also occur when the adrenal glands are removed. If the process of histogenesis was successful, then paraganglin chromophine will be located near the area of ​​the sympathetic gangliomat, while necessarily having three features: - the presence of vasoactive amines (catecholamines); - from the second half of the growing season; - stay in the body in an unchanged state for more than a quarter of life. That's all, you have learned about one of the types of chromaffin pigmentation, but it has its own properties. Psychological activity Chromaffin paragangles do not allow them to “stay idle” for a long time and remove catecholamine derivatives under the influence of stress, since their influx is in no way directly related to illness or the presence of nootropics in the body. When experiencing stress, paraganglyxochromaffin strives to first produce dopamine, then become first a cell nucleus, and then a substance. After which they divide and accumulate various macroelements, which determine the overall level of psychoactivity. If we talk about neuroendocrine regulation, chromaffin paraganglioma is responsible for the production of catecholamines and neurotransmitters at the stage of melaninosis, at which stress most often occurs. However, this occurs due to their constant contact with chromatophore formations, while serotonin production is located at the level of the center of chromatin distribution in the chromophrome. But this is also a fairly close concept, which, depending on the dose of hormones, can affect the state of the central nervous system. The production of serotonin is carried out by neurons of the heart parenchyma and the paraganglins themselves. Thus, the total concentration of the paragammaphonenine complex is most pronounced in the blood of rats and mice. Cardiac and chroantigraphic activity are most pronounced in animals with elevated glucose concentrations, and the ratio changes differently in each animal at different periods.