Platelet factor (PF) is a blood plasma glycoprotein adsorbed on the surface of platelets, which is chemically reminiscent of factor V, but its activity is much lower.
Platelet factor was discovered in 1955 and named thrombostenin for its ability to stimulate platelet aggregation, an important mechanism of blood clotting.
The functions of platelet factor are to regulate the process of blood clotting and the formation of a blood clot when blood vessels are damaged. It is involved in the activation of platelets and their ability to aggregate, which is necessary to stop bleeding.
However, platelet factor may also play a role in the development of cardiovascular diseases such as myocardial infarction and stroke. This is due to its ability to cause blood clots to form in blood vessels, which can impair blood flow and impair heart or brain function.
Thus, platelet factor is an important regulator of blood clotting, but its excess activity can lead to serious health consequences. Therefore, it is important to monitor the level of this glycoprotein in the blood and not allow it to deviate from the norm.
Platelet factor.
One of the most important functions of blood is to transport oxygen and nutrients from the heart to tissues and remove carbon dioxide from the body. One of the key cells in the transport process is the **platelet**. Platelets are tiny, anucleate, oval-shaped blood cells with a diameter of about 2-5 microns, containing a cytoplasmic substance and a glycocalyx membrane. The main part of the platelet cytoplasm is occupied by a granular network about 0.2 microns thick. And in the center of the cytoplasm is the tempocytic nucleus. Each cell is attached to the capillary wall by a special formation called von Willebrand adhesin. The platelet wall is a complex biochemical complex that includes many proteins and factors that regulate blood coagulation and thrombotic function