Plasmin (Plasmih), Fibrinolysin (Fibrinolysin)

Plasmin (Plasmih), Fibrinolysin (Fibrinolysin) is a plasma globulin that has an affinity for fibrin. Plasmin has a thrombolytic effect and reduces blood clotting (see Fibrinolysis). Plasmin is usually present in the blood in the form of plasminogen, its inactive precursor.



Plasmin (Plasmih) and Fibrinolysin (Fibrinolysin): Breakdown of clots and regulation of blood clotting

The human body has a complex system responsible for maintaining the balance between blood clotting and blood thinning. Various factors play an important role in this process, including plasmin (Plasmih) and fibrinolysin (Fibrinolysin). These two components are plasma globulins and play a key role in thrombolysis and regulation of blood clotting.

Plasmin is a plasma globulin that has an affinity for fibrin, the main component of blood clots. Fibrinolysin, in turn, is an enzyme that can destroy fibrin clots. Both of these components work together to provide effective thrombolysis and maintain normal circulation.

Plasmin is present in the blood as plasminogen, an inactive precursor of plasmin. Under the influence of various factors, such as thrombolysis activators or tissue plasminogen activator (t-PA), plasminogen is converted into active plasmin. Activated plasmin has a thrombolytic effect, that is, the ability to destroy fibrin clots.

Fibrinolysin, or fibrinolytic enzyme, is another important component of the clot-breaking system. It exhibits its activity by splitting fibrin clots into smaller fragments, which promotes their resorption. Thus, fibrinolysin improves tissue regeneration and restores normal blood circulation.

The combined action of plasmin and fibrinolysin plays an important role in the regulation of blood clotting. They prevent excessive clot formation and also destroy and resolve existing ones. This is especially important in cases of thrombosis, when the formation of clots exceeds their destruction.

The use of plasmin and fibrinolysin in medicine has a wide range of applications. They are used in the treatment of thrombosis, stroke, deep venous thrombosis and other conditions associated with bleeding disorders. Preparations containing plasmin and fibrinolysin can be used both systemically, administered intravenously, and locally, for example, in the form of gels and ointments.

However, despite all the benefits, you should consult your doctor before using these drugs. Like any medicine, plasmin and fibrinolysin have their own contraindications and side effects, which may be different for each patient.

In conclusion, plasmin (Plasmih) and fibrinolysin (Fibrinolysin) play an important role in the regulation of blood clotting. They provide a thrombolytic effect and destruction of fibrin clots, helping to maintain normal blood circulation. The use of these components in medicine may be useful for the treatment of thrombosis and other conditions associated with bleeding disorders. However, before use, you should consult your doctor to evaluate the indications, contraindications and possible side effects.



Plasmin and fibrinolysin are two important plasma globulins that play an important role in the blood clotting process. Plasmin is a proteolytic enzyme that breaks down fibrin, the main component of a blood clot. Fibrinolysin, on the other hand, is an enzyme that can break down fibrin and reduce blood clotting.

Plasmin is usually present in the blood as plasminogen, an inactive precursor that is activated when needed. When the level of fibrinogen in the blood increases, plasminogen is converted to plasmin, which leads to the destruction of blood clots and a decrease in blood clotting. This is due to the fact that plasmin is able to break down fibrin into smaller fragments, which facilitates its removal from the body.

However, if the level of fibrinolysis in the blood decreases, it can lead to blood clots and increased clotting. This may be due to various factors such as genetic mutations, medications, or injury. In such cases, additional measures may be required to maintain fibrinolysis levels and prevent blood clots.

In general, plasmin and fibrinolysin play an important role in maintaining the normal blood clotting process and preventing the formation of blood clots. However, their imbalance can lead to serious consequences such as thrombosis, so it is important to maintain their normal levels in the blood.