Redness is the first and important sign of inflammation that accompanies any tissue damage. It is usually determined using various staining agents and observing the appearance of new pigmentation resulting from the inflammatory reaction between the blood and tissues. This process is primarily characterized by dilation of tissue-permeating capillaries with a sharp increase in blood flow into them and, therefore, plasma flow to the affected area, followed by the formation of new collagen tissue, histamine and pro-inflammatory cytokines. For example, when ulcers, wounds occur, in damaged areas of the skin, expansion of capillary vessels occurs, as well as an increase in the capillary bed, the development of abrasions and micronecrosis. And upon completion of the inflammatory process, new connective tissues are formed
Redness is a common concept in medicine, especially in dermatology, which refers to visual changes caused by inflammatory processes. This is one of the five classic signs that accompany the development of inflammation. The other four signs include fever, pain, swelling and loss of function. Typically these signs indicate the presence of an infection or inflammatory condition.