Multiple lesions

Multiple lesions (ML) is a clinical term used to describe a number of lesions in different parts of the human body. The cause of multiple injuries and injuries is difficult to identify and analyze at the stage of early detection, which does not allow prompt response to them or prescribing adequate therapy. Thus, predicting severity and complications regardless of the time since injury in patients with MP remains difficult in modern conditions.

Multiple damage is a pathological condition of a part of the same organ or tissue or several different organs or tissues, resulting from the influence of the same causative factors or the influence of one factor. The term is widely used in the practice of traumatic injuries, as well as in diseases of internal organs and the nervous system. The concept of “multiple lesions” becomes especially important in case of combined diseases and infectious processes, therefore the terms “polypathic”, “polysymptomatic”, “systemic nature of the disease”, etc. may indicate the presence of multiple lesions in the patient. Multiple damage reflects the scale and severity of damage to an organ or tissues of the body in the presence of a large number of micro- and macroscopic changes not only in one organ, but also in many organs, up to a systemic reaction. Essentially, multiple injuries, especially combined injuries (injuries and diseases), begin when microcirculatory and neuroreflex imbalances occur, reflecting acute reactions to injury. It is during this period that decompensated disorders of carbohydrate, protein and fat metabolism occur, a discrepancy in time between the processes of cell proliferation, differentiation, healing and resorption of dead tissue in the damaged organ and activation of inflammatory processes in surrounding tissues. Stimulation of immunocompetent cells leads to the appearance of antigenic zones, their precipitation, aggregation and, ultimately, to aseptic inflammation.

Multiple lesions are a disease that affects several organs at the same time. This condition can occur for a variety of reasons, including infectious diseases, cancer, chemical and radioactive exposure, and trauma. In most cases, the consequences of multiple lesions are more serious and require long-term treatment.

Symptoms of multiple lesions may vary depending on the cause and location of the pathological changes. These may include pain, weakness, fever, cough, shortness of breath, fatigue, bleeding and other dysfunction of damaged organs. If the heart is damaged, arrhythmia, heart failure, and myocardial infarction are possible; in case of renal failure - increased level of creatinine in the blood and other changes; with liver disease - jaundice and increased liver enzymes.

Most multiple lesions are treated by a doctor who diagnoses the type of disease and selects the most appropriate treatment method. Most often, drugs are used that help restore the functions of damaged organs and stabilize the patient’s physiological condition. In addition, they apply