Pribram's Disease

Pribram's disease

Pribram's disease (postgastroenterostomy syndrome) is a disease described by the Austrian surgeon Victor Otto Pribram in 1914.

It is characterized by the development of secondary ulcers of the stomach and duodenum after gastroenteroanastomosis. The reason is the reflux of duodenal contents into the stomach through the anastomosis, which leads to irritation of the gastric mucosa.

Clinically manifested by epigastric pain, heartburn, nausea and vomiting, in severe cases - bleeding or perforation of the ulcer.

Diagnosis is based on medical history (previous gastroenterostomy), clinical picture and endoscopy data.

Treatment consists of prescribing a diet, antisecretory and enveloping drugs; if ineffective, repeat surgery with a change in the type of anastomosis. The prognosis is favorable with timely treatment.

Prevention - careful selection of patients for gastroenteroanastomosis and proper execution of the operation.



Pribramsky disease is a rare disease that is characterized by disruption of the nervous system and muscles as a result of surgery on the stomach or esophagus. This condition can lead to serious complications, including paralysis, loss of coordination, and loss of sensation and control of the legs and arms.

Symptoms of the disease can appear several weeks after surgery and are often in the nature of a temporary deterioration in the general condition of the patient. In most cases, symptoms occur suddenly and resolve on their own within a few hours or days.

Treatment of primordial disease may include the use of antidepressants, psychotherapy and special physical rehabilitation. You can also use painkillers and use specific exercise techniques to improve muscle function and prevent recurrence of pain.

One of the causes of Pribramsky disease is violations of surgical technique during the procedure for reconstructing the stomach and esophagus. Some surgical techniques do not properly align the muscles of the esophagus and stomach, which can lead to dysfunction and inflammation in the stomach tissue.

In general, primordial disease requires timely and effective treatment to avoid serious consequences for the patient's health, such as paralysis and impaired motor function. Remember that timely consultation with a doctor can significantly reduce the risk of developing this disease and facilitate treatment.