Van Den Bergh S Test

The Van Den Berg test is a test that allows you to determine the cause of a patient’s development of jaundice: whether it is caused by hemolysis, liver disease or bile duct disease.

A sample of the patient's blood is mixed with sulfanilic acid, hydrochloric acid and sodium nitrite. If the resulting solution immediately acquires a purple color, then a direct reaction has occurred, indicating that the cause of jaundice is some kind of liver disease or obstruction of the bile duct.

If the solution changes its color to purple only after adding alcohol to it, then an indirect reaction has occurred, indicating that the patient is developing hemolytic jaundice.



The Van Den Berg test (S-test) is a test to determine the cause of jaundice in a patient. This method allows you to determine whether jaundice is caused by hemolysis of the blood, obstruction of the bile ducts, or liver disease.

To perform the Van Den Berg test, a sample of the patient's blood is mixed with a certain amount of sulfanilic acid, hydrochloric acid and sodium nitrite. Depending on the reaction that occurs as a result of mixing these components, the cause of jaundice can be determined.

If the solution turns purple immediately after mixing, this indicates an indirect reaction and indicates the development of hemolytic jaundice, caused by the destruction of red blood cells. This can be caused by a variety of reasons, including autoimmune diseases or chemical exposure.

In the case of a direct reaction, when the solution changes its color to purple only after adding alcohol, this indicates a violation of the biliary tract or liver disease. This can happen when the bile ducts are blocked by a stone or other formation, or due to liver disease such as cirrhosis or hepatitis.

The Van Den Berg test is a simple and quick test that can help your doctor determine the cause of jaundice and prescribe appropriate treatment. However, it should be remembered that this test is not a definitive diagnosis and requires additional research to confirm the diagnosis.



The Van Den Berg test (VDBT) is a test that is used to determine the cause of a patient's jaundice. This test can determine whether jaundice is caused by hemolysis (destruction of red blood cells), liver disease, or obstruction of the bile ducts.

To perform a Van Den Berg test, a patient's blood sample is mixed with certain chemicals such as sulfanilic acid, hydrochloric acid and sodium nitrite. As a result of the reaction, the resulting solution changes its color from yellow to purple.

If a violet color of the solution appears immediately after mixing, this indicates a direct reaction, which indicates the presence of liver disease or bile duct obstruction. In this case, the patient must consult a doctor for further examination and treatment.

However, if the purple color appears only after the addition of alcohol, this indicates an indirect reaction, which indicates hemolytic jaundice. Hemolytic jaundice can be caused by various reasons, such as vitamin E deficiency, red blood cell damage, infectious diseases and others.

Thus, the Van Den Berg test is an important diagnostic test to determine the cause of jaundice. It allows you to quickly and accurately determine what disease causes jaundice in a patient, which allows you to start treatment in a timely manner and prevent possible complications.